IPTeL Tracking ID: MPS-IAP-2015-015
The invention relates to biomedical devices, in particular microfluidic catridge for performing microscopic analysis of biological samples.
BACKGROUND
Currently, clinical microscopy is used for studying the structure and features of biological samples for diagnosis. It is a time consuming process which requires skilled people. In addition, it also suffers from drawbacks like improper sample preparation leading to error and difficult to do single cell analysis. Recent advances in the field of cell analysis uses flow cytometry to get high throughput. It is performed using flow cytometers which are expensive compared to conventional techniques and does not provide information on morphology of cells. Imaging flow cytometers (IFC) overcomes the limitation by providing morphological analysis of cells with high throughput. IFCs contain microfluidic catridge having mixing, filter and imaging zones. Presently, catridges are having straight parallel channel design leading to very high velocity of sample and reagent which requires high quality expensive camera to do imaging.
TECHNOLOGY
The invention provides an improved microfluidic catridge for imaging flow cytometry (IFC) system. This catridge provides high throughput and does not require expensive camera, making the IFC system suitable for point of care diagnostics.
Key features of the invention:
- Uses low frame rate image sensor
- Optimized imaging throughput
- Does not require expensive camera
- Enables point of care diagnostics
- Enhances performance of bright field based imaging counters.